GC-MS analysis and Molecular docking of Quercetin compounds of Phytolacca octandra with the target protein of infection causing Staphylococcus aureus

Phytolacca octandra is a perennial usually about 1m high herb, dense and erect in full sun. As only few reports were available on the studies bioactive compounds various activities octandra, present study focuses bio active attributed to antibacterial activity plant extracts by Gas Chromatography – Mass Spectrometry (GCMS) molecular docking methods. Antibacterial of showed maximum inhibitory zones 21mm, 18mm, 19mm, 19mm 20mm against respective organisms for 25mg/ml acetone extracts. The outcome that was exposed GC-MS analysis, presence 20 more compounds. most identified have anti-oxidant are Dodecane, Octadecane Octacosane. other major extract Cyclohexen-oxopropyl, 1,2-Benzenedicarboxylic acid.The overall energies target protein, rhamnolipids biosynthesis 3-oxoacyl-[acyl-carrier-protein] reductase with quercetin number hydrogen bonds presented study; report revealed –8.01Kcal/Mol binding 8 bonding between compound, rhlG infection causing pathogen Staphylococcus aureus.